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5 Ways Saxenda Helps with Weight Loss & how to use it Safely
Christy Horniman edited this page 2026-08-21 10:38:37 +08:00
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This is great information - thank you! This has been the only med that’s worked for me after 3 different ones. I’m curious though what happens (biochemically speaking) when you stop taking Saxenda. Any thoughts you can share? I’ve been using Saxenda for 5 weeks and am down 15 pounds. The nausea went away after 5 days. I was told to increase the dosage each week and MedicGLP Official now I’m up to 3mg daily. I have developed my own way of using it, which I describe in this post, and when used in the way I recommend the entire goal is to be able to stop the medication and keep the weight off. But that only works if you can reverse the resistant syndromes that potentiate weight gain (leptin and insulin resistance) while you use it. So, if you just use it as a weight loss tool by itself and don’t address these issues, there’s a high chance you’ll regain the weight you lose once you stop taking it.


First of all, thank you for all you do for us! I have Hashimoto’s and I’m on Naturethroid, Liothyronine, and LDN, and I’ve been AIP since 2015. After a very stressful year and a half, I gained (very quickly) 50 lbs. The gaining has finally stopped, I started Keto on top of AIP (its doing nothing), I’m not terribly hungry, but I’m not losing. I tested my fasting insulin (3.2) and leptin (68.6). So seems I don’t have an insulin resistance problem but I do have a leptin resistance problem. Is that even possible? And would Saxenda be good for me to try given the insulin vs. I’m getting desperate. I think I could convince my doctor to prescribe it. I found it very difficult to find a Dr in Australia that will actually measure Leptin. However, I persevered and did find one. My Leptin is 160 (Aust range is 5 to 11) which I know is ridiculously high.


I have about 30kg to lose. I have paid for your program, and I am very good at sticking to such regimes, so I don’t think it will be too difficult. I took your info to my Dr and am now on Saxenda. I realise everyone is different, supplement for a balanced lifestyle but how long could I expect to see results with such high Leptin levels? I have tried so many things which have never worked and it gets really discouraging. My thyroid is OK, my P4/E2 Ration is 33.3 (saliva testing) and my cortisol isn’t too bad. I want to have realistic expectations so I don’t feel disappointed. Most people, even with severe leptin resistance, should see weight loss by the 4-8 week mark. Weight loss may be slower with leptin resistance that high, but you should still see some movement by that time. Have you had any patients experience developing gastroparesis because of Saxenda?


It has been like a miracle for me but has always seemed to make me constipated. Recently my acid reflux is getting worse and MedicGLP Official my stomach gets a hard/full feeling in between my ribs. I don’t know if this is just a sign the reflux is bad or bigger problems. Any advice appreciated. Also any advice for maintaining weight loss after Saxenda? Is there a "maintenance dose"? I’ve been using this for over a month at first I had an bad reaction to my injection site on my stomach. So, I now object in my thigh & it’s much better. I’m using my dosage as instructed and I’ve lost 30lbs. Now I did make a lifestyle change eating low calories a day and a strict workout routine. My question is how do I stop the feeling of nausea. It doesn’t seem to get any better! Not only that, I’m always tired and fatigue too. I’m an athletic person and exercising and healthy eating gives me energy just not with this med.


I struggle to find energy daily and I fight the horrible pain in my stomach daily. I would be careful with your calorie restriction. If you lose weight due to that method then it will come back once you stop taking the medication. In regards to nausea, that is usually dose dependent. If you adjust your dose it should subside. I had a sleeve gastrostomy done in 2013 and lost 32 kg in 1year but slowly regaining the weight since 2016 and I gained 15kg . My doctor started me on Saxenda 2 weeks ago and I am taking 3mg dose now . During the 1st week , I lost 1.5kg but now I am gaining back the 1.5kg already . May I know if this should be happening ? I am not eating much at all since post op. I am concerned with my Low metabolism rate of 1100kcal and the body compensation strategy .